Syllabus query



Academic Year/course: 2021/22

592 -

18870 - ORGANIC CHEMISTRY

This is a non-sworn translation intended to provide students with information about the course


Information of the subject

Code - Course title:
18870 - ORGANIC CHEMISTRY
Degree:
592 -
Faculty:
104 - Facultad de Ciencias
Academic year:
2021/22

1. Course details

1.1. Content area

ORGANIC CHEMISTRY

1.2. Course nature

Optional

1.3. Course level

Grado

1.4. Year of study

XX

1.5. Semester

First semester

1.6. ECTS Credit allotment

6.0

1.7. Language of instruction

English

1.8. Prerequisites

BU students must have taken at least one of the following options:

 

Option 1: CH101 (General Chemistry 1) and CH102 (General Chemistry 2).

Option 2: CH101 (General Chemistry 1) and CH110 (General and Quantitative Analytical Chemistry).

Option 3: CH111 (Intensive General and Quantitative Analytical Chemistry 1) and CH112 (Intensive General and Quantitative Analytical Chemistry 2).

 

UAM students must have taken any of the following courses:

 

16476 (Química -Grado en Ciencias Ambientales-)

16535 (Química -Grado en Ingeniería Química-)

16575 (Química -Grado en Ciencias de la Alimentación-)

18201 (Química -Grado en Bioquímica-)

18422 (Química General –Grado en Nutrición, Biología o Física-)

1.9. Recommendations

-

1.10. Minimum attendance requirement

Attendance to classes is strongly recommended. Absences which may result from illnesses, religious holidays, serious accidents, etc must be immediately notified to the Faculty coordinator. To receive full credit a student must document the reason for their absence (for example a signed and stamped doctor’s note). Please note that having scheduled exams in another subject is not a valid excuse

1.11. Subject coordinator

Victoria Martinez Diaz

1.12. Competences and learning outcomes

1.12.1. Competences

-

1.12.2. Learning outcomes

Important learning goals that the student will wish to achieve are:

(1) understanding the implications of the covalent bond in the structure of organic compounds

(2) how to name organic compounds systematically

(3) the ability to deduce the structures of organic molecules by interpreting their nuclear magnetic resonance spectra

(4) developing an appreciation for the interplay of an organic molecule’s three-dimensional structure and that molecule’s chemical properties

(5) the ability to predict the properties and reactivity of organic compounds

1.12.3. Course objectives

(Taken from BU’s Organic Chemistry I Syllabus)

Organic chemistry studies the properties of the compounds of carbon, which alone of all the chemical elements can form the numerous, strong, and directional bonds essential to the construction of biomolecules such as fats, carbohydrates, proteins and nucleic acids. This course focuses on gaining an understanding of the fundamental concepts of the science. A few reactions (acid–base, radical halogenation, addition to carbon–carbon multiple bonds, nucleophilic substitution and elimination) are covered. The relevance of organic chemistry to biological systems, medicine, environmental science and industry is discussed. In the laboratory portion of the course, students gain experience in conducting organic reactions, purifying products, and interpreting and reporting organic chemical phenomena.

1.13. Course contents

 

Structure and Bonding in Organic Compounds

(1)

1.1. Electronic structure.

1.2. Ionic and covalent bonding. Lewis                     theory and diagrams. Formal charges.

1.3. Inductive effects. Dipole moment. Polar covalent bonds.

1.4. Hybridization: s and p bonding

1.5. Drawing organic molecules

1.6. Delocalization of p electrons. Resonance.

1.7. Resonance structures. Drawing resonance forms.

1.8. Non-equivalent resonance structures. Rules.

1.9. Aromaticity (MO theory).

Polar Covalent Bonds: Acids and Bases

(2)

2.1. Bronsted definition of acids and bases

2.2. Lewis definition of acids and bases

2.3. Organic acids and organic bases

2.4. Acid and base strength

2.5. Nucleophiles and electrophiles

Alkanes and Cycloalkanes

(3)

3.1. Alkanes: Nomenclature. Structural isomers.

4.2. Alkanes: Chirality. Optical activity. Cahn-Ingold-Prelog rules. Enantiomers and diastereoisomers. Meso compounds. Conformational isomers.

4.3. Cycloalkanes: Nomenclature. Cis/trans isomerism.

4.4. Cycloalkanes: Stability and ring strain. Conformational isomers.

4.5. Representative examples and physical properties of alkanes and cycloalkanes.

4.6. Reactivity of alkanes: halogenation reaction (a radical reaction)

Structural determination (Nuclear Magnetic Resonance Spectroscopy)

(4)

4.1. NMR: principles and spectral features (intensity, chemical shift and couplings).

4.2. Proton and carbon spectra

Haloalkanes

(5)

5.1. Nomenclature. Representative examples. Physical properties. Polar covalent bonding.

5.2. Nucleophilic substitution reactions

5.3. Elimination reactions

Alcohols and epoxides

(6)

6.1. Nomenclature. Representative examples. Physical properties (acidity and basicity revisited).

6.2. Reactivity: dehydration, oxidation, OH-protection, epoxide ring-opening.

Alkenes

(7)

7.1. Nomenclature. Cis/trans isomerism.

7.2. Representative examples. Physical properties.

7.3. Relative stability. Catalytic Hydrogenation.

7.4. Electrophilic addition reactions:

     7.4.1. Mechanism; carbocation stability;

               regiochemistry; stereochemistry.

     7.4.2. Addition of hydrogen halides,

                halogens and water.

     7.4.3. Hydroboration, epoxidation,

               dihydroxylation, ozonolysis

7.5. Radical additions.

Alkynes

(8)

8.1. Nomenclature. Representative examples. Physical properties.

8.2. Reactivity: catalytic hydrogenation; hydration.

8.3. Alkyne acidity: acetylide anions.

8.4. Alkylation of acetylide anions

 

Laboratory contents:

Experiment

Related info

Introduction

Safety and Preparation

Using Extraction to Isolate the Analgesic Active Principles of a

Sample

Acid-base extraction, distillation, recrystallization, melting point, TLC, NMR.

Chromatography as a Method for Drug Separation

TLC, NMR.

Separation of the Enantiomers of Ibuprofen

Reflux, vacuum filtration, recrystallization, polarimetry.

 

1.14. Course bibliography

  • Organic Chemistry 6th Edition by W. H. Brown, C. S. Foote, B. L. Iverson, E. V. Anslyn (Brooks Cole).
  • Organic Chemistry 2nd Edition, by David Klein (Wiley)
  • Introduction to Organic Laboratory Techniques. A Microscale Approach, 3rd Ed. – BU custom edition, W.B. Saunders, 2000.
  • Molecular Modeling Computer Programs.
  • e-Learning UAM (Moodle)

2. Teaching-and-learning methodologies and student workload

2.1. Contact hours

 

#hours

Contact hours (minimum 33%)

105 h

Independent study time

45 h

2.2. List of training activities

Activity

# hours

Lectures

50

Seminars

 

Practical sessions

20

Clinical sessions

 

Computer lab

 

Fieldwork

 

Laboratory

25

Work placement

 

Supervised study

 

Tutorials

 

Assessment activities

 

Other (exams)

10

3. Evaluation procedures and weight of components in the final grade

3.1. Regular assessment

Mid-term exams (adapted from BU’s Organic Chemistry I Syllabus)

 

Three 80-minute exams are scheduled during the class time. These mid-term exams are graded on a 10-point basis. Your lowest lecture exam score will be dropped in calculating your course grade. No make-up lecture exams are given for any reason: please do not ask to take a make-up mid-term exam nor ask to take it at other than the scheduled date and time. Do not make travel plans that conflict with the lecture exams.

 

 

3.1.1. List of evaluation activities

Evaluatory activity

%

Final exam

25

Continuous assessment

50

Lab exam

25

 

 

Mid-term exams (adapted from BU’s Organic Chemistry I Syllabus)

 

Three 80-minute exams are scheduled during the class time. These mid-term exams are graded on a 10-point basis. Your lowest lecture exam score will be dropped in calculating your course grade. No make-up mid-term exams are given for any reason: please do not ask to take a make-up mmid-term exam nor ask to take it at other than the scheduled date and time. Do not make travel plans that conflict with the lecture exams.

 

Final exam (adapted from BU’s Organic Chemistry I Syllabus to Spanish Law)

 

A cumulative 4-hour final exam is scheduled at the end of semester. Final exam is graded on a 10-point basis. See the “Incompletes” section of this syllabus for policies concerning missed final exams.

 

Lab grades (adapted from Dresden w/BU’s Organic Chemistry I Syllabus to Spanish Law)

 

 The grade for the student performance at the laboratory is based on 1) pre-lab and post-lab questions, experimental skill and ability to record observations about the experiments. Part of your skill grade will be based on results (e.g. ability to obtain the product) and part will be based on your technique (adherence to safety rules, cleanliness and organizational skills) as assessed by your teaching fellows. 2) 50% of the lab grade will be obtained from a written exam scheduled for the two last hours of the lab week.  

 

Grades (adapted from BU’s Organic Chemistry I Syllabus to Spanish Law)

 

Course grades are calculated by the following formula:

 

CH203 Grade = (Mid-term1 + Mid-term2 + FE + Lab Exam) / 4

 

where Mid-term1 and Mid-term2 are the scores of your two highest of three Mid-term exams, FE is the score of your final exam, and Lab is your lab score. All individual scores are based on 10 points. The maximum score is 10. The minimum score to pass is 5.0

 

Spanish grade ranges are:

Lowest (no pass): 0-4,9: Suspenso (SS).

Low (pass): 5,0-6,9: Aprobado (AP).

Intermediate: 7,0-8,9: Notable (NT).

High: 9,0-9,9: Sobresaliente (SB).

Highest: 10: Matrícula de Honor (MH)

3.2. Resit

Make-up exams (taken from Dresden w/BU’s Organic Chemistry I Syllabus)

        

There are no make-up exams whatsoever.

 

Make-up Labs (adapted from Dresden w/BU’s Organic Chemistry I Syllabus)

 

Students are expected to perform all experiments. There are no make-up labs whatsoever in this abroad program since you are leaving the country right after the lab ends. Absences which may result from illnesses, serious accidents, etc must be immediately notified to the Faculty coordinator. To receive full credit a student must document the reason for their absence (for example a signed and stamped doctor’s note). Please note having scheduled exams in another subject is not a valid excuse. A student who does not have a documented excuse will receive a maximum grade of 7.0 for the lab absence.

 

3.2.1. List of evaluation activities

valuatory activity

%

Final exam

 

Continuous assessment

 

4. Proposed workplan

Week

 

Topic’s name

(entry)

1

 

Structure and Bonding in Organic Compounds  (1)

2

 

Polar Covalent Bonds: Acids and Bases  (2)

3 - 4

 

Alkanes and Cycloalkanes  (3)

4 - 5

 

Structural determination (Nuclear Magnetic Resonance Spectroscopy)  (4)

6

 

Haloalkanes  (5)

7

 

Alcohols and epoxides  (6)

8 -10

 

Alkenes   (7)

11 and 13

 

Alkynes  (8)

 

12

 

Laboratory (see bellow)

 

14

 

Final remarks and exam

 

Date*

(Week 12)

Experiment

12

(11/26-11/30)

Introduction

Using Extraction to Isolate the Analgesic Active Principles of a

Sample

Chromatography as a Method for Drug Separation

Separation of the Enantiomers of Ibuprofen

Lab exam (Make-up lab)

 


Curso Académico: 2021/22

592 - Asignaturas transversales

18870 - ORGANIC CHEMISTRY


Información de la asignatura

Código - Nombre:
18870 - ORGANIC CHEMISTRY
Titulación:
592 - Asignaturas transversales
Centro:
104 - Facultad de Ciencias
Curso Académico:
2021/22

1. Detalles de la asignatura

1.1. Materia

-

1.2. Carácter

Optativa

1.3. Nivel

Grado

1.4. Curso

XX

1.5. Semestre

Primer semestre

1.6. Número de créditos ECTS

6.0

1.7. Idioma

English

1.8. Requisitos previos

-

1.9. Recomendaciones

-

1.10. Requisitos mínimos de asistencia

-

1.11. Coordinador/a de la asignatura

Victoria Martinez Diaz

1.12. Competencias y resultados del aprendizaje

1.12.1. Competencias

-

1.12.2. Resultados de aprendizaje

-

1.12.3. Objetivos de la asignatura

-

1.13. Contenidos del programa

-

1.14. Referencias de consulta

-

2. Metodologías docentes y tiempo de trabajo del estudiante

2.1. Presencialidad

 

#horas

Porcentaje de actividades presenciales (mínimo 33% del total)

 

Porcentaje de actividades no presenciales

 

2.2. Relación de actividades formativas

Actividades presenciales

Nº horas

Clases teóricas en aula

 

Seminarios

 

Clases prácticas en aula

 

Prácticas clínicas

 

Prácticas con medios informáticos

 

Prácticas de campo

 

Prácticas de laboratorio

 

Prácticas externas y/o practicum

 

Trabajos académicamente dirigidos

 

Tutorías

 

Actividades de evaluación

 

Otras

 

3. Sistemas de evaluación y porcentaje en la calificación final

3.1. Convocatoria ordinaria

-

3.1.1. Relación actividades de evaluación

Actividad de evaluación

%

Examen final (máximo 70% de la calificación final o el porcentaje que figure en la memoria)

 

Evaluación continua

 

3.2. Convocatoria extraordinaria

-

3.2.1. Relación actividades de evaluación

Actividad de evaluación

%

Examen final (máximo 70% de la calificación final o el porcentaje que figure en la memoria)

 

Evaluación continua

 

4. Cronograma orientativo

-