Syllabus query



Academic Year/course: 2022/23

592 -

18871 - CELL BIOLOGY

This is a non-sworn translation intended to provide students with information about the course


Information of the subject

Code - Course title:
18871 - CELL BIOLOGY
Degree:
592 -
Faculty:
104 - Facultad de Ciencias
Academic year:
2022/23

1. Course details

1.1. Content area

-

1.2. Course nature

Optional

1.3. Course level

Grado

1.4. Year of study

XX

1.5. Semester

First semester

1.6. ECTS Credit allotment

6.0

1.7. Language of instruction

English

1.8. Prerequisites

-

1.9. Recommendations

Previous knowledge on biology is required. Students from Boston University are expected to have followed CAS BI 108 and CAS CH 102 or equivalents. Students from Universidad Autonoma de Madrid should have taken a previous course of General Biology, equivalent to a last High School year (2º Bachillerato) or First Degree Course at University.

1.10. Minimum attendance requirement

Attendance is highly recommended for theoretical lessons and is mandatory for seminars.

1.11. Subject coordinator

Rocio Gomez Lencero

1.12. Competences and learning outcomes

1.12.1. Competences

-

1.12.2. Learning outcomes

-

1.12.3. Course objectives

1.- Acquire basic knowledge of eukaryote cell components: molecules, genomes and organelles.

 

2.- Understand the main processes operating in cells: genome expression, protein synthesis, intracellular trafficking, membrane transport, cell movement, cell communication, cell adhesion, cell proliferation and differentiation.

 

3.- Develop data analysis competences and critical thinking.

 

4.- Acquire basic skills for communication of scientific contents.

1.13. Course contents

FIRST PART: INTRODUCTION. ORGANIZATION AND PROCESSING OF GENETIC INFORMATION

 

  1. Introduction: features of eukaryote cells. Origin and evolution of cells.
  2. Fundamentals of cell biochemistry: sugars, lipids, proteins and nucleic acids.
  3. Research tools in cell biology: cell cultures, model organisms, molecular techniques, cellular and organism modification, microscopy techniques.
  4. Cell nucleus: nuclear envelope, chromatin structure and nuclear compartmentalization.
  5. Genome organization: types of DNA sequences and their proportions and origin.
  6. DNA: replication, repair and recombination.
  7. RNA: transcription and processing.
  8. Proteins: synthesis, folding and degradation.

 

SECOND PART: CELL SURFACE AND ORGANELLES

 

  1. Cell membranes: composition, organization and dynamics.
  2. Membrane transport: passive diffusion, passive transport, active transport, endocytosis and exocytosis.
  3. Protein sorting and transport I: endoplasmic reticulum and the secretory pathway.
  4. Protein sorting and transport II: Golgi apparatus, vesicular transport and lysosomes.
  5. Bioenergetics and metabolism: mitochondria, chloroplasts, cellular energetics and peroxisomes.
  6. Cell surface: cellular interactions and extracellular matrix.
  7. Cell signaling: signaling molecules and receptors, transduction mechanisms and signaling pathways.

THIRD PART: CYTOSKELETON AND CELL PROLIFERATION

 

  1. Actin microfilaments: organization, polymerization, regulation and functions.
  2. Intermediate filaments: organization, polymerization, regulation and functions.
  1. Microtubules: organization, polymerization, regulation and functions.
  1. Cell cycle: phases of the cell cycle, regulation by CDK-cyclin complexes, checkpoints.
  2. Mitosis: phases and events of mitosis, checkpoints, APC, cytocinesis.
  3. Cell differentiation and death: stems cells, differentiation of cells in tissues, events of apoptosis, intrinsic and extrinsic apoptotic pathways.
  4. Cancer: cellular approaches to cancer study and therapy.

SEMINARS PROGRAM

 

            The program of the course is complemented with seminars. These will mainly focus on the discussion of Cell Biology topics through the review of classical experiments or the presentation of recent research on specific topics.

1.14. Course bibliography

The organization and contents of the course will mainly follow the book:

  • Cooper, G.M. and Hausman, R.E. The Cell, A Molecular Approach. 7th Edition. Sinauer Associates, 2016.

 

Other recommended bibliography:

  • Alberts, B., Bray, D., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P. Molecular Biology of the Cell. B. 6th Ed. Garland Science, 2015.
  • Alberts, B., Bray, D., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P. 2013. Essential Cell Biology. Garland Science. 4th Edition.
  • Hardin, J., Bertoni, G.P. and Kleinsmith, L.J. 2011. Becker's World of the Cell. Pearson/Benjamin Cummings. 8th Edition.
  • Lodish, H. Kaiser, C.A., Bretscher, A., Amon, A., Berk, A., Krieger, M., Ploegh, H and Scott, M.P. 2013. Molecular cell biology. 7th Edition. Macmillan.
  • Pollard, T.C., Earnshaw, W.C. and Lippincott-Schwartz, J. 2007. Cell Biology. Elsevier. 2nd Edition.

2. Teaching-and-learning methodologies and student workload

2.1. Contact hours

 

#hours

Contact hours (minimum 33%)

59

Independent study time

91

2.2. List of training activities

ACTIVITY

Attendance hours

Autonomous work hours

TOTAL

LECTURES

44

80

124

SEMINARS AND CASED-BASED LEARNING LESSONS

9

9

18

EXAMS

6

2

8

TOTAL WORKLOAD:

59

91

150

LECTURES

The goal of the course is to understand the fundamental principles of cell biology. The aim of the lectures is to convey to the students the theoretical contents of the composition and functions of cells. Lectures will have a duration of 50 minutes, where the lecturer will present in a simply way the contents of each topic always encouraging students to participate with questions and comments.

 

SEMINARS

The theoretical program will be accompanied by 6 seminars of 1 hour each. These seminars seek to encourage students analyze the experimental nature of contemporary research in the Cell and Molecular Biology and understand its relationship with the fundamental background information given during the theoretical lectures. Students will prepare a short lecture (30-45 minutes) in small groups (3-4 people) about one topic related to the contents of the course. The rest of the students could engage in a discussion about the topic. After the talk, the speakers will provide a set of questions about their talk to be included in a seminar test at the end of the course.

 

CASED-BASED LEARNING LESSONS

        The course includes one session of three hours of case-based learning, where students develop team working, communication, and professional skills. The case study used in class will be integrated into the syllabus of the module, adapted to the biomedical interests of the BU-UAM students, and will encourage autonomous learning and teamwork.

 

TUTORIALS

The University recommends that students attend tutorials for the resolution of questions regarding the content of the course. These tutorials will be held individually and upon request with the teacher assigned.

3. Evaluation procedures and weight of components in the final grade

3.1. Regular assessment

Student’s final grading will be based on the understanding of theoretical concepts (80%) and participation in seminars (20%).

 

THEORY

Theory contents will be divided in three parts. There will be two mid-term evaluations and one final evaluation scheduled, covering the complete syllabus. These exams will review the knowledge and skills collected by the students during the course. The 80% of the grade that corresponds to theory concepts will be based on the result of the 3 examinations, with the two mid-term evaluation exams weighing 25% of the total grade and the final evaluation exam being the remaining 30% of the total grade.  One of the questions of the exam will be based on the concepts worked during the case-based learning session

 

SEMINARS

The 20% of the total grade will be based on seminars. A 10% will be accounted by student skills for understanding and communicating the concepts exposed in their talk. Other 10% will be accounted by a quiz including questions from all of the seminars.

3.1.1. List of evaluation activities

Summary of the assessment rates

 

Percentage of the final grade

First evaluation exam

25%

Second evaluation exam

25%

Final evaluation exam

30%

Seminars

20%

TOTAL

100%

3.2. Resit

-

3.2.1. List of evaluation activities

Evaluatory activity

%

Final exam

 

Continuous assessment

 

4. Proposed workplan

*This calendar is tentative.

 

THEORY/SEMINARS

 

FIRST PART: INTRODUCTION. GENETIC INFORMATION ORGANIZATION AND PROCESSING

 

     - Theory lessons: 17 hours

     - Discussion seminars: 2 hours

     - Review and mid-term evaluation exam: 2 hours

 

SECOND PART: CELL SURFACE AND ORGANELLES

     - Theory lessons: 16 hours

     - Discussion seminars: 2 hours

     - Review and mid-term evaluation exam: 2 hours

 

THIRD PART: CYTOSKELETON AND CELL PROLIFERATION

 

     - Theory lessons: 12 hours

     - Discussion seminars: 4 hours

- Review and final evaluation exam: 3 hours

 

Week

 

Contents

 

Contact hours

Independent study time

1

Introduction

Organization and processing of genetic information

3

6

2

Organization and processing of genetic information

4

6

3

Organization and processing of genetic information

4

6

4

Organization and processing of genetic information

4

6

5

Organization and processing of genetic information

Seminars

Mid-term evaluation

7

6

6

Cell surface and organelles

5

6

7

Cell surface and organelles

5

6

8

Cell surface and organelles

Seminar

4

6

9

Cell surface and organelles

Seminar

Mid-term evaluation

5

6

10

Cytoskeleton and cell proliferation

3

6

11

Cytoskeleton and cell proliferation

Seminar

4

6

12

NO ACTIVITIES (Organic Chemistry laboratory)

 

6

13

Cytoskeleton and cell proliferation

3

6

14

Cytoskeleton and cell proliferation

FINAL EVALUATION

9

6

 


Curso Académico: 2022/23

592 - Asignaturas transversales

18871 - CELL BIOLOGY


Información de la asignatura

Código - Nombre:
18871 - CELL BIOLOGY
Titulación:
592 - Asignaturas transversales
Centro:
104 - Facultad de Ciencias
Curso Académico:
2022/23

1. Detalles de la asignatura

1.1. Materia

-

1.2. Carácter

Optativa

1.3. Nivel

Grado

1.4. Curso

XX

1.5. Semestre

Primer semestre

1.6. Número de créditos ECTS

6.0

1.7. Idioma

English

1.8. Requisitos previos

-

1.9. Recomendaciones

-

1.10. Requisitos mínimos de asistencia

-

1.11. Coordinador/a de la asignatura

Rocio Gomez Lencero

1.12. Competencias y resultados del aprendizaje

1.12.1. Competencias

-

1.12.2. Resultados de aprendizaje

-

1.12.3. Objetivos de la asignatura

-

1.13. Contenidos del programa

-

1.14. Referencias de consulta

-

2. Metodologías docentes y tiempo de trabajo del estudiante

2.1. Presencialidad

 

#horas

Porcentaje de actividades presenciales (mínimo 33% del total)

 

Porcentaje de actividades no presenciales

 

2.2. Relación de actividades formativas

Actividades presenciales

Nº horas

Clases teóricas en aula

 

Seminarios

 

Clases prácticas en aula

 

Prácticas clínicas

 

Prácticas con medios informáticos

 

Prácticas de campo

 

Prácticas de laboratorio

 

Prácticas externas y/o practicum

 

Trabajos académicamente dirigidos

 

Tutorías

 

Actividades de evaluación

 

Otras

 

3. Sistemas de evaluación y porcentaje en la calificación final

3.1. Convocatoria ordinaria

-

3.1.1. Relación actividades de evaluación

Actividad de evaluación

%

Examen final (máximo 70% de la calificación final o el porcentaje que figure en la memoria)

 

Evaluación continua

 

3.2. Convocatoria extraordinaria

-

3.2.1. Relación actividades de evaluación

Actividad de evaluación

%

Examen final (máximo 70% de la calificación final o el porcentaje que figure en la memoria)

 

Evaluación continua

 

4. Cronograma orientativo

-